Ashwagandha for Stress and Anxiety: Systematic Review

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These scientific studies are for informational purposes only.

The presented research results are NOT approved Health Claims under EU Regulation (EC) No 1924/2006. Only Health Claims officially approved by EFSA may be used for product advertising.

Non-approved Health Claims are legally impermissible and may lead to warnings.

✅ Check approved claims: [EU Health Claims Register](https://ec.europa.eu/food/safety/labelling_nutrition/claims/register/public/)

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## Summary

A recent meta-analysis by Lopresti AL et al. from 2024 investigates the anxiolytic effects of Ashwagandha and was published in the Journal of Integrative Medicine.

Study Background

This systematic review analyzes randomized controlled trials on the effects of Ashwagandha on stress and anxiety parameters.

Key Findings

The meta-analysis shows: - Significant stress reduction: Cortisol levels reduced by 25-30% - Anxiety relief: Hamilton Anxiety Scale significantly improved - Dosage: 300-600 mg extract twice daily - Onset of effect: Measurable after 4-6 weeks

Methodology

As a meta-analysis, this work combines data from 12 randomized controlled trials with over 1000 participants.

Practical Relevance for Dietary Supplement Manufacturers

These research results are relevant for: - Product development: Standardized root extract (withanolides) - Study results: The research shows certain effects (no approved claims) - Dosage: 300-600 mg twice daily - Quality control: At least 5% withanolides

Source

The full study is freely available on Europe PMC.

Authors: Lopresti AL, Smith SJ, Drummond PD Year: 2024 Journal: Journal of Integrative Medicine PMCID: PMC10891811 PMID: 38350735

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*Note: This summary is for informational purposes. The presented study results are not approved Health Claims. For detailed information, please consult the original source.*