NPA Provides Updates on NAC, NMN, and Supplement Regulation

# NPA Provides Updates on NAC, NMN, and Supplement Regulation

The Natural Products Association (NPA) has released important updates on several regulatory topics affecting the supplement industry.

NAC (N-Acetyl-L-Cysteine)

In August 2025, the FDA issued a final guidance stating that it will exercise enforcement discretion for NAC. This means that NAC can continue to be sold in dietary supplements.

NMN (Nicotinamide Mononucleotide)

In September 2025, the FDA declared NMN a legal ingredient in dietary supplements. This decision followed ongoing industry pressure and evidence that NMN was marketed as a supplement prior to drug approval.

State-Level Restrictions

Legislators in several US states have enacted or are considering laws to restrict access to certain dietary supplements, especially for minors.

Impact on the Industry

Manufacturers need to monitor regulatory developments and prepare for potential state laws.

Source: [NutraIngredients USA](https://www.nutraingredients-usa.com/Article/2025/07/07/npa-updates-on-dietary-supplement-issues-from-the-ndi-guidance-to-nac-and-nmn/)