HMB (β-Hydroxy-β-Methylbutyrate): JISSN Position Stand

## Summary

The JISSN Position Stand by Wilson JM et al. from 2013 provides evidence-based recommendations on HMB supplementation and was published in the Journal of the International Society of Sports Nutrition.

Study Background

This position stand analyzes the scientific literature on β-Hydroxy-β-Methylbutyrate (HMB), a leucine metabolite with anti-catabolic effects.

Key Findings

The position stand shows: - Optimal dose: 3g/day (divided into 3x1g doses) - Timing: 30-60 minutes before training or with meals - HMB forms: Free acid (HMB-FA) vs. calcium salt (HMB-Ca) - Muscle protection: Especially effective during calorie deficit and training - Strength gains: Synergistic effects with creatine and protein

Methodology

The position stand is based on clinical studies and meta-analyses of HMB supplementation in trained and untrained individuals.

Scientific Context (No approved Health Claims)

Please note: The following information describes scientific study results. They do not constitute recommendations for health claims and must not be used as such.

These position stand findings are relevant for: - Scientific product development: HMB-FA vs. HMB-Ca formulations - Study results: Anti-catabolic mechanisms - Dosing studies: 3g/day divided into 3 doses - Transparency: Combinations with creatine and protein

Source

The full position stand is freely accessible.

Authors: Wilson JM, Fitschen PJ, Campbell B, Wilson GJ, Zanchi N, et al. Year: 2013 Journal: Journal of the International Society of Sports Nutrition DOI: 10.1186/1550-2783-10-6

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*Note: This summary is for informational purposes only. The presented study results are not approved health claims. For detailed information, please consult the original source.*